Have you done the fundamentals first, like checking your AV cable, ground, checking your AV ports for corrosion or looseness, solder joints, etc.? Do you have any spare boards that you can swap to try and narrow down the problem? Is there any sound at all coming from the Gamecube out port (hum, buzz, etc.) If there is a hum or buzz it may well be a short somewhere. Check for any excessive heat emanating from areas of the board or chips. use some flux and heat and note any heat spots. If all else fails, replace the PSU as that has been known to create such audio difficulties.